Bayer flea and tick control

The product only works when in direct contact with the skin. If you put it between the shoulder blades and it stays on the coat, that's no good. Best bet is to flip the dog over and rub it on the belly. Use a pair of rubber gloves. If the dog isn't real keen to being flipped over and handled like that, put it from the shoulder blades to the tip of the tail, then rub it in a little.

I'd have to go back and do the math, but if memory serves me correctly due to the percentages of Imidacloprid in the Bayer Tree & Shrub (1.47%) vs Bayer Advantage (9.1%) I use about 20cc's of the Tree & Shrub on each dog.