In my last yard we had a deadly strain of parvo that would kill grown pups in 24 hours that had been vaccinated. Did a ton of research and found a company called NeoTech that makes a LIVE virus vaccine. Used them on three sets of pups in that yard and haven't had a parvo case again. Watch this video and you will see how weak the 5 and 7 way vaccines are.
http://youtu.be/ZKitt_QAxBg