If you can put her in the pen with the one that's in heat, and if you can put a horny male next to them and let the male and female that's not in intermingle everyday and the more he "stimulates" her by licking and mounting will more than likely trigger her hormones into estrous....
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Ive got her between two male dogs ,, one of which I am going to breed her too,, guess they aint doin nuthin for her lol.....will have to wait and see,,, I just aint never had to give one the shot before and didn't know what the pro's and cons were if I had too... thanks