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Author Topic: Fenbendazole - Panacur/Safe-Guard  (Read 20581 times)
Mark T
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« on: June 12, 2009, 11:29:44 am »

After the Ivermectin post I got thinking/cranking the mg/kg on other items I am giving my dogs and here is what I came up with.  Once again my math might be off, however the mg percentages are the most important part here.

Panacur C Canine Dewormer
Panacur® (fenbendazole) Granules 22.2% contains the active anthelmintic, fenbendazole. The chemical name of fenbendazole is methyl 5-(phenylthio)-2-benzimidazole carbarnate. The CAS Registry Number is 43210-67-9.
Panacur® Granules 22.2% contains 222 mg/g of fenbendazole.

FOR DOGS - 50 mg/kg (22.7 mg/lb.) daily for 3 consecutive days for the removal of ascarids (Toxocara canis, Toxascaris leonina), hookworms (Ancylostoma caninum, Uncinaria stenocephaia), whipworms (Trichuris vulpis), and tapeworms (Taenia pisiformis).

DIRECTIONS - The daily dosage of 50 mg/kg (22.7 mg/lb) (so a 70 lb dog needs 1,589 mg of Fenbendazole x3 days to be effective) can be achieved as follows:  Using a gram scale, weigh out 1 gram of Panacur® (fenbendazole) Granules 22.2% for each 4.44 kg or 10 lbs. body weight.  Daily dosages must be repeated for 3 consecutive days. Mix the appropriate amount of drug with a small amount of the usual food: dry dog food may require slight moistening to facilitate mixing with the drug.
TOXICOLOGY DATA - Panacur® Granules 22.2% did not cause toxicity when administered to weaned pups at doses equal to 5 times the recommended daily dose (which means 22.7 mg x 5 = 113.5mg per lb)and for 2 times the duration of treatment.
Vs.

Safe-Guard® Paste 10% Equine Dewormer
Safe-Guard® (fenbendazole) Paste 10% contains the active anthelmintic, fenbendazole. Each gram of Safe-Guard® Paste 10% contains 100 mg of fenbendazole and is flavored with artificial apple-cinnamon liquid. The antiparasitic action of Safe-Guard® Paste 10% is believed to be due to the inhibition of energy metabolism in the parasite.
Size - 25 gram paste 10% (100 mg/g). Tube size is 4" and the nozzle is 1-1/2”. Which means the whole tube contains 2,500 mg of Fenbendazole, and half the tube contains 1,250 mg of Fenbendazole.

PANACUR (FENBENDAZOLE 25GM PASTE 10% HORSE DEWORMER -  Panacur (fenbendazole) 10% contains the active anthelmintic, fenbendazole . the chemical name of fenbendazole is methyl 5-(phenylthio)-2benzimidazolecarbamate. Each gram of Panacur Fenbendazole paste 10 % contains: 100 mg of fenbendazole and is flavored with artificial apple-cinnamon liquid. Panacur (fenbendazole) paste 10% is administered orally at a rate of 2.3 mg/lb. (5 mg/kg) for the control of large strongyles, small strongyles, and pin worms. One syringe will deworm a 1,100 lb. horse For foals and weanlings (less than 18 months of age) where ascarids are a common problem, the recommended dose is 4.6 mg/lb. (.10 mg/kg) One syringe will deworm a 550 lb. horse. So 100mg per gram + 25 gram tube = 2,500 mg for the whole tube and 1,250mg for half a tube.

So my calculations based from the Panacur C dog wormer and the Panacur/Safe-Guard Horse wormer is that to get the recommended mg per dog you would need to use more than half a tube of the horse wormer for 3 days.  A Horse only needs 2.3 mg- 4.6mg/lb and dogs need 22.7mg/lb to be effective.  What does everyone else think about these calculations?  I would like someone feedback.
Best Regards,
Mark T
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Mark T
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« Reply #1 on: June 15, 2009, 08:25:54 am »

Any feedback?
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BRC
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« Reply #2 on: June 15, 2009, 08:31:07 am »

Pretty accurate.I always used 1/2 tube one day and the rest next day.
Zimectrin works better.Also keep a bottle  HOOTS CHOICE WORMER from Hoot Gibson.
Works as good as any I have seen.10.00-6 oz,can`t give too much to young pups either.
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Mark T
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« Reply #3 on: June 15, 2009, 11:14:37 am »

BRC,
I appreciate the reply.  I will look at Zimectrin and Hoot's choice wormer.
Mark T
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« Reply #4 on: June 15, 2009, 12:49:16 pm »

Is it just me or does that shade of blue over the ETHD background make you go cross-eyed.
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« Reply #5 on: June 15, 2009, 01:17:59 pm »

Cull Buck,
I would have to agree.  The blue is very bad.  I should have chose another color.
Regards,
Mark T
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« Reply #6 on: June 25, 2009, 08:54:48 pm »

Have you ever used the safeguard liquid wormer for goats? Seems to be alittle more cheaper than the paste horse wormer and the same stuff except in liquid form. Being a bad tasting liquid, alittle harder to give, lots of slobbers.
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« Reply #7 on: June 26, 2009, 12:04:26 am »

Mark, I have been using the safeGuard cattle Worming tube that goes in the Caulking gun type deal for several years, I give one click per dog every dog no matter small or large. I have had a few times a year where I have to power dose for three days in a row to take care of the dogs because of outbreak- infestations, but I feel that this method has been very good for my dogs and everytime I have had any of the vets I use do a fecal, the dogs have been negative for any worms. I did once have a problem with Whipworms and that was when using Strongid every 30 days, The cure was Panacur for 3 days in a row, and that took care of it.

I just had my newest puppy have a problem with anemia, I wormed her Tuesday with safeguard, and that did not take care of it, so Today she went to vet for Fecal test to determine it was Coccidiaosis, but No worms at all.
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« Reply #8 on: June 26, 2009, 01:58:41 pm »

Krystal what did the vet give for the cochcidiosis?  Every litter I have had they get that around 6 weeks old and then again around 2-3 months and then they seem to be ok and I never treat them for it but I can see where if they were to get it while it is this hot it could really stress them.  Ususally just loose stool with mucous and lethargic for 3-5 days and sometimes they throw up a white mucous looking liquid and they drop a little weight.  I watch them closely to make sure that is all that happens and after the second time it is like their body knows how to fight it.  Just would like to know how to treat it in the future.
Thanks,
MG
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« Reply #9 on: June 26, 2009, 02:15:34 pm »

Matt

 my vet gave me albon to use for cochcidiosis
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« Reply #10 on: June 26, 2009, 09:31:29 pm »

Yep, Albon is the only thing I have ever been given by any of the vets for that, it works as long as you don't have other underlying problems such as worms and too far gone with anemia.

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AnthonyB
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« Reply #11 on: June 28, 2009, 10:39:06 pm »

Have you ever used the safeguard liquid wormer for goats? Seems to be alittle more cheaper than the paste horse wormer and the same stuff except in liquid form. Being a bad tasting liquid, alittle harder to give, lots of slobbers.

did the math on that one and its the same as the horse wormer, so its really more expensive.
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« Reply #12 on: June 30, 2009, 01:54:58 pm »

AnthonyB


My math on the Safeguard using these numbers from TSC are as follows...let me know if your #'s differ as math is not my strongest subject.  Based on my numbers, we have been using the goat dewormer on our dogs.

Goat - 100ml - $17.99 - treats 4347#  or .21 per 50# dose

Cattle - 290g - $44.99 - treats 12,100# or    .19 per 50# dose

Cattle - 92g - $24.99 - treats 3838# or    .33 per 50# dose

Horse - 25g - $7.99 - treats 1100# or  .36 per 50# dose
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« Reply #13 on: July 10, 2009, 11:30:23 am »

you can take the liquid corid an give an you can take an put it in ur water bucket
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« Reply #14 on: July 10, 2009, 11:30:11 pm »

I've found the safe-guard (10% suspension) liquid to be the most cost effective and the easiest to dose accurately.

It comes in three sizes, the larger you buy, the cheaper it is per unit:

125ml
http://www.jefferslivestock.com/ssc/product.asp?CID=2&pf_id=0029013

1000ml and 1 gallon
http://www.jefferslivestock.com/ssc/product.asp?CID=2&pf_id=16380
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